Could Glycine Receptors be the Pathway for Cannabinoids to Relieve Pain?

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Some studies prove that CBD is very effective in the reduction of inflammation and neuropathic pain without the occurrence of analgesic tolerance. Analgesic tolerance means the patient needs and increase of the drugs to relieve pain. This makes it important to find something that avoids analgesic tolerance because the higher a dose, the more damaging side-effects occur. Because CBD is able to keep stable doses during treatment, it makes it a very positive treatment to manage chronic pain. Further research indicates that CBD is involved in the pain pathway. CBD targets the glycine receptors in the spinal cord causing the expected inhibitory effects in the pain pathway to the brain.

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