Does Cannabis Tolerance Influence Medicinal Benefits?

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For some, building-up a tolerance can be a significant pain in the ass. For others, it could mean an achievement. But when it comes to the point that you have to pack your joint tighter, or that you have to smoke more to get high, you are in the process of building-up tolerance. So, what is happening? A cannabis expert from the Yale School of medicine discovered that the CB1 receptors change over time when you consume cannabis. The CB1 receptors are where the THC cannabinoids interact.

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